WebPaired box 8 Recommended Applications Product Description Monoclonal Antibody against Human PAX8 Alternative Gene Names - Open Datasheet. Price. $505.00. Product Number. AMAb91488. Unit Size. Concentration. Lot dependent. Availability >10 in Stock. Ships. Ready to Ship. Share by E-mail Add to ... Webpaired box gene 8; paired box protein Pax-8; paired domain gene 8; Description The PAX8 gene product is a member of the paired box (PAX) family of transcription factors. It is a transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such ...

WikiGenes - PAX8 - paired box 8

Webpaired box 8. Normal Function. The PAX8 gene belongs to a family of genes that play ... Pax-8-PPAR-gamma fusion protein in thyroid carcinoma. Nat Rev Endocrinol. 2014 … WebMay 25, 2016 · Paired box 8 (PAX8) is a crucial nephric-lineage transcription factor, and its aberrant expression has been detected in various types of cancer including Müllerian carcinomas. PAX8 antisense RNA 1 (PAX8-AS1), a potential regulator of PAX8, contains specific single nucleotide polymorphisms (SNPs) that may represent expression … how much super should i have at 54

Paired Box-8/Peroxisome Proliferator-Activated Receptor-γ …

WebCharacteristics. Nature: Nuclear transcriptional regulator in the paired-box family expressed during organogenesis of the thyroid gland, kidney, and Müllerian tract. Gene and structure: Chromosomal localization 2q13, Molecular weight of the unprocessed precursor 48 kDa, of five isoforms 31-42 kDa. Occurrence and function: PAX8 is a ... This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins which contain a paired box domain, an octapeptide, and a paired-type homeodomain. The PAX gene family has an important role in the formation of tissues and organs during … See more Paired box gene 8, also known as PAX8, is a protein which in humans is encoded by the PAX8 gene. See more • Pax genes See more • PAX8+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • "Xenbase Gene: Summary for pax8, species: Xenopus tropicalis" See more The PAX8 gene is also associated congenital hypothyroidism due to thyroid dysgenesis because of its role in growth and development of the thyroid gland. A mutation in the PAX8 gene could prevent or disrupt normal development. These mutations can … See more • Poleev A, Fickenscher H, Mundlos S, Winterpacht A, Zabel B, Fidler A, Gruss P, Plachov D (November 1992). "PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors". Development. 116 (3): 611–23. See more WebAug 19, 2013 · PAX8 is a member of the pair-box (PAX) family of transcription factor genes. Recent studies showed that PAX8 is a useful marker to distinguish gynecologic cancers from non-gynecologic malignancies including malignant mesotheliomas, cancers of gastrointestinal origin and breast cancers, which are common confusion sources in … how much super should i have at 52