Lecithin-cholesterol acyltransferase-like 4
NettetGene ID: 105107838, updated on 3-Jun-2024. Summary Other designations. lecithin-cholesterol acyltransferase-like 4 NettetLecithin cholesterol acyltransferase deficiency is a disorder of lipoprotein metabolism. The disease has two forms: Familial LCAT deficiency, in which there is complete LCAT deficiency, and Fish-eye disease, in which there is a partial deficiency.. Lecithin cholesterol acyltransferase catalyzes the formation of cholesterol esters in lipoproteins.
Lecithin-cholesterol acyltransferase-like 4
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NettetGene ID: 101504088, updated on 9-Jun-2024. Summary Other designations. lecithin-cholesterol acyltransferase-like 4 Lecithin–cholesterol acyltransferase (LCAT, also called phosphatidylcholine–sterol O-acyltransferase) is an enzyme, in many animals including humans, that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, eventually … Se mer Click on genes, proteins and metabolites below to link to respective articles. Se mer • Lecithin cholesterol acyltransferase deficiency • Acyl-CoA:cholesterol acyltransferase (ACAT) Se mer • Lecithin+Cholesterol+Acyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural information available in the PDB for UniProt: P04180 (Phosphatidylcholine-sterol acyltransferase) at the Se mer • Dobiásová M, Frohlich J (1999). "Advances in understanding of the role of lecithin cholesterol acyltransferase (LCAT) in cholesterol transport". Clin Chim Acta. 286 (1–2): 257–71. Se mer
NettetLecithin–cholesterol acyltransferase (LCAT) deficiency is an autosomal recessive disorder. 24 The mutations are on the LCAT gene located on chromosome 16q22. 25 … NettetLecithin:cholesterol acyltransferase (LCAT) is a key enzyme that catalyzes the esterification of free cholesterol in plasma lipoproteins and plays a critical role in high …
NettetThe plasma 1ecithin:cholesterol acyltransferase reaction JOHN A. GLOMSET Department of Medicine and Regional Primate Research Center, University of Washington, Seattle, Washington 98105 ABSTRACT Evidence for the existence of a plasma lecithin : cholesterol acyltransferase is reviewed with emphasis not only on the lipid reactants, … NettetGene ID: 103971400, updated on 19-Aug-2024. Summary Other designations. lecithin-cholesterol acyltransferase-like 4
NettetA number sign (#) is used with this entry because Norum disease is caused by homozygous or compound heterozygous mutation in the lecithin:cholesterol acyltransferase gene (LCAT; 606967) on chromosome 16q22. The LCAT gene is also mutant in fish-eye disease ( 136120 ).
NettetIntroduction. Lecithin cholesterol acyltransferase (LCAT) (EC2.3.1.43), a lipoprotein-associated enzyme, is a key player in the reverse cholesterol transport (RCT) pathway, which promotes the transfer of excess cellular cholesterol from peripheral tissues to the liver for excretion [].Genetic disorders of LCAT are associated with low levels of high … can you use therefore to start a sentenceNettet1. nov. 1996 · The potential of a recombinant adenovirus approach for treatment of subjects with LCAT gene defects as well as patients with low plasma levels of apo A-I and HDL cholesterol is established. BACKGROUND Overexpression of human lecithin-cholesterol acyltransferase (LCAT) in transgenic mice results in an increase of the … can you use thera tears with contactsNettetLecithin cholesterol acyltransferase (LCAT) is a glycoprotein that has both a phospholipase A2 and an acyltransferase action. It is essential for the normal … can you use the ring doorbell insideNettet26. mai 2000 · DOI: 10.1074/jbc.C000144200 Corpus ID: 26890344; A Lecithin Cholesterol Acyltransferase-like Gene Mediates Diacylglycerol Esterification in … can you use thermacell indoorsNettetLecithin cholesterol acyltransferase (LCAT) is a glycoprotein that has both a phospholipase A2 and an acyltransferase action. It is essential for the normal … british bites boltonNettetGene ID: 103498271, updated on 17-Oct-2024. Summary Other designations. lecithin-cholesterol acyltransferase-like 4 can you use thermalite blocks outsideNettetThe risk score formula was as follows: risk score = 0.06324 × relative expression of SPINK1 + 0.18856 × relative expression of TXNRD1 + (−0.15727) × relative expression of LCAT + (−0.098) × relative expression of PZP. Table 1 Univariate Cox regression analysis: P <0.05. Table 2 Coefficients of the four-gene signature for the risk score. british bites