Cisplatin versus carboplatin

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August undefined, 2024

WebJun 1, 2016 · Carboplatin ( cis -diammine-cyclobutanedicarboxylato-platinum (II)) was initially believed to have “comparable” therapeutic activity with cisplatin but is associated … WebMar 30, 2024 · Rao S, Jones M, Bowman J, Tian C, Spano JP. POD1UM-303/InterAACT 2: A phase III, global, randomized, double-blind study of retifanlimab or placebo plus carboplatin-paclitaxel in patients with locally advanced or metastatic squamous cell anal carcinoma. Front Oncol. 2024 Aug 24;12:935383. doi: 10.3389/fonc.2024.935383. …

Carfilzomib combined with rituximab, ifosfamide, carboplatin, and ...

WebAdvanced NSCL patients treated with carboplatin or cisplatin doublet with third-generation chemotherapy drugs showed equivalent overall survival, one-year survival, and response rate. Regarding adverse events, carboplatin caused more thrombocytopenia, and cisplatin caused more nausea/vomiting. WebMay 25, 2024 · Carboplatin is preferred over cisplatin in the extensive stage disease because of its favorable toxicity profile. Data comparing the efficacy of carboplatin with … simply broadband vodafone

Carboplatin- or Cisplatin-Based Chemotherapy in First-Line …

WebWe investigated the activity and safety of first-line GEMOX compared with gemcitabine–carboplatin (GCb) in cisplatin-ineligible patients with advanced UCC. Methods: Treatment-naive, cisplatin-ineligible patients with advanced UCC were randomly assigned to GEMOX (gemcitabine 1000 mg/m 2 , oxaliplatin 100 mg/m 2 on day 1 [D1] … WebCisplatin Versus Carboplatin. Carboplatin is another platinum derivate with a tenfold longer half-life than cisplatin. Due to structural differences from cisplatin, it exhibits lower reactivity and slower DNA binding kinetics in vitro. In clinical studies, the nonhematologic tolerability of carboplatin is superior to that of cisplatin, making ... WebCisplatin carries a higher toxicity profile, including nausea, vomiting, neuropathy, renal insufficiency, and alopecia in comparison to carboplatin. When the goal of … simply brows \u0026 lashes newtown

Randomized Trial of Intravenous Versus Intraperitoneal …

A prospective randomized study comparing the efficacy between …

WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel … WebApr 4, 2024 · Balancing factors were planned platinum agent (cisplatin vs carboplatin), preoperative radiologically or pathologically assessed nodal involvement (N0 vs N1 vs N2 vs N3), status of microscopic surgical margins (positive vs negative), and treating centre. Participants were randomly allocated (1:1) either surveillance or chemotherapy. simply brows and lashes camberwellWeb"Carboplatin is now being used more often than cisplatin because it can be given on an outpatient basis. It causes less kidney damage, hearing loss, nausea and vomiting and peripheral nerve damage (manifested by muscle weakness and numbness or tingling). Unfortunately, it does have more bone marrow toxicity than cisplatin." simply broadband uk

"WebThere have been limited data comparing outcomes of carboplatin vs. cisplatin-based CRT, particularly in elderly. Material and methods: From the Surveillance, Epidemiology and End Results-Medicare registry, we identified 1878 patients >65 years of age with unresected stage III NSCLC that received concurrent CRT between 2002 and 2009. " - Cisplatin versus carboplatin

Cisplatin versus carboplatin

Adjuvant chemotherapy in upper tract urothelial carcinoma …

WebApr 4, 2024 · Days 1–5: 5-FU 800mg/m 2 /day by continuous infusion for 5 days; plus. Days 1–5: Radiotherapy: 2Gy repeated every other week for 7 cycles. Carboplatin + paclitaxel (Category 2B)11. Day 1 ...

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WebDec 1, 2024 · Methods. In this open-label, randomized, phase III study, newly diagnosed patients with advanced NSCLC were initially randomized (R1, 1:1) to receive first-line treatment with cisplatin 75 mg/m 2 plus docetaxel 75 mg/m 2 (DC75) or 60 mg/m 2 (DC60) for up to 4 cycles. Patients without progression were further randomized (R2, 1:2) to best … WebApr 4, 2024 · Carboplatin belongs to a class of medications known as platinum-containing compounds. It works by stopping or slowing the growth of cancer cells. Carboplatin is …

WebComparison of single agent versus combined chemotherapy in previously treated patients with advanced urothelial carcinoma: a meta-analysis Xiao-Jun Wu, Yi Zhi, Peng He, Xiao-Zhou Zhou, Ji Zheng, Zhi-Wen Chen, Zhan-Song Zhou Institute of Urinary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of … WebOct 20, 2024 · The majority of data in this space are derived from small phase 2 trials. 16,17 In this retrospective cohort study, we attempt to evaluate the efficacy of carboplatin vs cisplatin in both LS-SCLC and …

WebApr 2, 2012 · Cisplatin is associated with more GI adverse effects, neurotoxicity, and renal function impairment, and its administration requires a prolonged hydration, 5, 6 but carboplatin is associated with more myelosuppression. Although the mechanisms of action are similar, it is unclear whether carboplatin and cisplatin have the same clinical efficacy. WebOct 20, 2024 · Quality versus quantity of life in the treatment of patients with advanced small-cell lung cancer? a randomized phase III comparison of weekly carboplatin and …

WebMar 14, 2024 · A study of 51 patients who received carboplatin with concurrent radiotherapy showed similar response and toxicity profiles when compared with historical controls who had been chosen to receive cisplatin and concurrent radiation. 14 Furthermore, an observational, noninferiority study of patients with locally advanced …

WebApr 16, 2024 · All four planned doses of cisplatin or carboplatin were received by 82.5% of the patients in the pembrolizumab-combination group and by 74.3% of those in the placebo-combination group; 76.5% and ... ray price cherokee cowboy dvd release dateWebAdvanced NSCL patients treated with carboplatin or cisplatin doublet with third-generation chemotherapy drugs showed equivalent overall survival, one-year survival, and response … simply brows south yarraWebHotta K, Matsuo K. Long-standing debate on cisplatin- versus carboplatin-based chemotherapy in the treatment of advanced non-small cell lung cancer. J Thorac Oncol. 2007;2(1):96. 4. Hamdi T, Latta S, Jallad B, Kheir F, Alhosaini MN, Patel A. Cisplatin-induced renal salt wasting syndrome. simply brows lane coveWebJun 1, 2016 · In comparison with carboplatin, the use of cisplatin has been more extensively evaluated in the systemic management of endometrial cancer. A recent … ray price collectors choiceWebApr 10, 2024 · We stratified the study participants according to 4 factors: 1) primary disease site (oral cavity/oropharynx vs. non-oral cavity/oropharynx), 2) treatment modality (post-operative or definite CCRT), 3) treatment schedule (weekly vs. 3-week), and 4) chemotherapy regimen (cisplatin vs. carboplatin). ray price city lights videoWebNovember 2010 edited August 2024 in Head and Neck Cancer #1 Hi, My husband, Joe, has 6 more days of radiation and 1 more chemo (Cisplatin 100mcg/m2) to go. He has developed all of the typical side affects posted here and hopefully can get through the rest of treatment and onto recovery. simply brushed vintageWebThe dose-limiting side effect for cisplatin is nephrotoxicity, for carboplatin it is myelosuppression, and for oxaliplatin it is neurotoxicity. Other common side effects … ray price chicago pd